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EN Hyperthermia
Hyperthermia Overview
Hyperthermia is a type of treatment in which body tissue is heated to as high as 113 °F to help damage and kill cancer cells with little or no harm to normal tissue. Hyperthermia to treat cancer is also called thermal therapy, thermal ablation, or thermotherapy.Hyperthermia to treat cancer is not widely available. But at some centers it is used, along with other treatments such as radiation therapy and chemotherapy, for advanced cancers. It has been used to treat these types of advanced cancers such as appendix cancer, bladder, brain cancer, breast, cervical cancer, esophageal cancer, head and neck cancer, liver cncer, lung cancer, melanoma, mesothelioma, sarcoma, rectal cancer
Hyperthermia is almost always used with other forms of cancer treatment. Many clinical trials have shown that hyperthermia, when used with treatments such as radiation therapy and chemotherapy, helps shrink tumors and may make it easier for them to kill cancer cells.
Hyperthermia treatment
Hyperthermia treatment can be local, regional or whole-body hyperthermia, depending on the extent of the area being treated.● Local hyperthermia
Local hyperthermia is used to heat a small area like a tumor. Very high temperatures are used to kill the cancer cells and destroy nearby blood vessels. In effect the area that is exposed to the heat. The higher the temperature duration of exposure, the greater the effect seen within tissues. Thermal ablation comprises the treatments where very high temperatures cause irreversible damage to cancer cells whereas smaller rises in temperature constitute mild hyperthermia. Radio waves, microwaves, ultrasound waves, and other forms of energy can be used to heat the area.
● Regional hyperthermiaIn regional hyperthermia a part of the body, such as an organ, limb, or body cavity is heated. It isn’t hot enough to destroy the cancer cells outright. It’s usually combined with chemotherapy or radiation therapy.
One approach, called regional perfusion or isolation perfusion, the blood supply to a part of the body is isolated from the rest of the circulation. The blood in that part of the body is pumped into a heating device and then pumped back into the area to heat it. Chemotherapy can be pumped in at the same time. This technique is being studied as treatment for certain cancers in the arms or legs, such as sarcomas and melanomas. Another one to regional hyperthermia is deep tissue hyperthermia. This treatment uses devices that are placed on the surface of the organ or body cavity and produce high energy waves directed at a certain area. These devices give off radiofrequency or microwave energy to heat the area being treated.
● Whole-body hyperthermia
Whole-body heating is being studied as a way to make chemotherapy work better in treating cancer that has spread (metastatic cancer). Body temperature can be raised by using heating blankets, warm-water immersion (putting the patient in warm water), or thermal chambers (much like large incubators). People getting whole-body hyperthermia are sometimes given sedation (medicine to make them feel calm and sleepy) or even light anesthesia. A person’s body temperature may be raised as if they had a fever, which is sometimes called fever-range whole-body hyperthermia. Studies suggest that this may cause certain immune cells to become more active for the next few hours and raise the levels of cell-killing compounds in the blood. Some researchers take the body temperature higher, around 107°F(41°C), for short periods of time. 
Benefits of Hyperthermia
Hyperthermia treatment’s benefit is that it can target your body with an exact temperature. It also has a very accurate target. Doctors use hyperthermia as a part of the cancer treatment strategy and not as the entire strategy. There are many benefits to using heat therapy:● Hyperthermia treatment is great for treating cancers that have already been treated with radiation.
● Hyperthermia is good for small tumors that can be targeted locally.
● This treatment is also good if you have cervical, head, and neck cancer.
● It’s also good for melanoma or other locally advanced cancers.
● Another benefit of hyperthermia treatment is how your body responds to the treatment. There’s an improved immune response when you undergo this treatment. Your body activates cells that boost your immunotherapy.
