Overview

The goal of cancer treatment is to achieve a cure for cancer patients, allowing them to live a normal life span. It may or may not, depending on their specific situation, If a cure isn't possible, their treatments may be used to shrink their cancer or slow the growth of their cancer to allow them to live symptom free for as long as possible. In addition to the three major methods of cancer treatment, namely surgery, radiotherapy and chemotherapy, targeted therapy is in the ascendant and due to the understanding of the physiology and molecular mechanism of cancer cells, small molecule therapies have sprung up like mushrooms, including CAR T-cell immunotherapy treatment brings new hope to this ultimate goal.

Cancer Treatment Plan

Treating cancer can involve a number of different specialists, medical practices, and caregivers. It’s important that every person involved in the process fully understands the patient’s cancer, treatments, symptoms, and goals. That is why SERO recommends all our patients maintain an updated cancer treatment plan. A written cancer treatment plan outlines all aspects of a patient’s cancer and treatments. This ensures every provider and caretaker understands the patient’s history and goals and can provide treatment accordingly. When you are diagnosed with cancer, your first step is to choose your treatment options. Doing so may involve the opinions of multiple specialists, friends, and loved ones. Once you decide on a treatment or treatments, you and your doctors will plan and schedule them. These planning and scheduling decisions make up your treatment plan.For cancer treatment plan details..(Read More>) // Download the reference of cancer treatment plan document(Download>)

Three cancer treatment methods

There are three cancer treatment methods as below
1.Primary treatment:
  The goal of a primary treatment is to completely remove the cancer from your body or kill all the cancer cells. Any cancer treatment can be used as a primary treatment, but surgery is the most common primary cancer treatment for the most common types of cancer.

2.Adjuvant treatment:
  The goal of adjuvant therapy is to kill any cancer cells that may remain after primary treatment in order to reduce the chance that the cancer will recur. Any cancer treatment can be used as an adjuvant therapy. Common adjuvant therapies include chemotherapy, radiation therapy and hormone therapy.

3.Palliative treatment:
  Palliative treatments may help relieve side effects of treatment or signs and symptoms caused by cancer itself. Surgery, radiation, chemotherapy and hormone therapy can all be used to relieve symptoms. Other medications may relieve symptoms such as pain and shortness of breath.



AI in Cancer Treatment

    Despite major advances in treatment over the past decades, cancer remains one of the most deadly diseases worldwide. Early detection and care are the best tools doctors have against the disease. However, challenges including high false-positive rates and difficult predicting treatment success can slow down the process. Healthcare professionals are finding ways to apply the latest developments artificial intelligence AI to the treatment of cancers. There are five of these innovative technologies:
1) Improving lung cancer screening
    Lung cancer screening with the use of computed tomography (CT) is highly effective in reducing the mortality rate of lung cancer.
2) Ruling out false positives and negatives
    AI-boosted detection methods may result in quicker treatment for the patients that need it, while sparing those who may have been incorrectly considered at high risk for cancer with previous diagnostic methods.
3) Predicting immunotherapy success
    Immunotherapy is a relatively new treatment for cancer that uses drugs to boost the human immune system and help it fight off malignant cells. New AI tool combinated with regular CT scans, an algorithm could be used to identify patients who are most likely to respond well to immunotherapy
4) Improving radiation therapy
    Radiation therapy is one of the most effective treatments available for many different types of cancer. However, it is extremely hard on the body, and it is often difficult to predict how patients will react. AI artificial intelligence was successfully used to help doctors plan where to target radiation therapy and forecast how well a patient is likely to hold up to the effects.
5) Personalized cancer treatment
    The AI model used by the clinic works with a combination of medical records and patient health history, along with CT scans. It builds customized programs for each patient based on a mathematical model that estimates how well they would respond to certain treatments.

Precision medicine

    Precision medicine called personalized medicine or personalized care is a way to offer and plan specific care for patients, based on the paatient's genes (or the genes in cancer cells). Precision medicine looks at how a specific gene mutation might affect a person's risk of getting a certain cancer or, if already have cancer, how genes (or genes in their cancer cells) might affect treatment.

Gene mutations

    Each cell in a patient's body has DNA which contains genes. Genes are the instruction cells use to make proteins needed to keep body working normally. When cells divide to make new cells, the genes inside those cells are copied. A gene change happens when there's a mistake in the copying process. Sometimes these changes come from a parent. But they can also happen sometime later in life for gene changes. Some gene changes can be harmful, while others may not cause any problems.

Gene mutation caused cancer

    All cancers are caused by a genetic change or mutation of some kind. Cancer cells are mutated versions of normal cells, meaning something changed in a normal cell to make it turn into a cancer cell.
    While we don't yet know all the genes and mutations that could be involved in the development of cancer, there are some we know about and can test for. Depending on the type of mutation, an abnormal gene change might make a person more likely to develop a certain cancer.and if they already have cancer, the abnormal gene might mean that the cancer may not respond well to a certain type of treatment or drug. In some paient with cancer, a specific gene mutation might mean that their prognosis outcome is better or worse than someone with the same cancer who does not have that gene change.


Gene diagnosis and treatment

    Patient with a cancer diagnosis, their tumor might be tested for certain types of gene changes or proteins made from those gene changes. This testing can provide information about how their cancer grows and spreads. It also called biomarker tests (chromosome tests, gene tests, or biochemical tests) It might be done using a blood or saliva sample, biopsy tissue, or body fluids.
    In some cancers, the gene testing done on a tumor can affect treatment choices. This is because certain gene changes can affect how a tumor responds to certain treatments and some tumors have gene changes that are different from other tumors of the same type. For treatment, the major goal is to give a target gene mutation treatment, without causing too many side effects, and to avoid giving treatments that might not work.

Types of cancer where precision medicine is used

    It's important that precision medicine is not used for every cancer. Treatments will be customized to the specific gene changes in each patient’s cancer. Some of the more common cancers where precision medicine is being used to help with treatment decisions including Colorectal cancer, Breast cancer, Lung cancer, Certain types of leukemia, Certain types of lymphoma, Melanoma, Esophageal cancer, Stomach cancer, Ovarian cancer, and Thyroid cancer.

Biomarker test

  There are many types of cancer treatment, The types of treatment that one receives will depend on the type of cancer one has and how advanced it is. Some people with cancer will have only one treatment. But most people have a combination of treatments. When one need treatment for cancer, one has a lot to learn and think about. It is normal to feel overwhelmed and confused. But, talking with doctor and learning about the types of treatment for more control.

  Before to do cancer treatment, there is an important testing from doctor called Biomarker testing which is a way to look for genes, proteins, and other substances(called biomarkers or tumor markers) that can provide information about cancer. It can help doctor choose the best cancer treatment for patient. Please get more detail information form below Biomarker testing and cancer treatment types.

Cancer treatment types

  The most important cancer treatment types are immunotherapy, CAR-T, bone marrow (Stem cell) transplant, surgery, chemotherapy, radiation therapy, hormone therapy, targeted therapy, cryoablation, radiofrequency ablation, hyperthermia, photodynamic therapy and clinical trials.

Cancer Treatment Types

 

A biological molecule found in blood and tissues that is a sign of a normal or abnormal process. A biomarker may be used to see how well the body responds to a treatment for a disease.
Biomarker testing is a way to look for genes, proteins that can provide information about cancer. Each patient’s cancer has a unique pattern of biomarkers. Biomarker testing may help you and your doctor choose a cancer treatment for you. Biomarker testing is different from genetic testing that is used to find out if someone has inherited mutations that make them more likely to get cancer.
Biomarker

 

Immunotherapy is a type of cancer treatment that helps your immune system fight cancer. The immune system helps your body fight infections and other diseases. It is made up of white blood cells and organs and tissues of the lymph system.
Immunotherapy is a type of biological therapy. Biological therapy is a type of treatment that uses substances made from living organisms to treat cancer. Several types of immunotherapy are used to treat cancer. These included Immune checkpoint inhibitors, T-cell transfer therapy, Monoclonal antibodies, Treatment vaccines and Immune system modulators.
Immunotherapy

 

A type of treatment in which a patient's T cells are changed in the laboratory so they will attack cancer cells. T cells are taken from a patient’s blood then hen the gene for a special receptor that binds to a certain protein on the patient’s cancer cells is added to the T cells in the laboratory. The special receptor is called a chimeric antigen receptor (CAR). Large numbers of the CAR-T cells are grown in the laboratory and given to the patient by infusion. CAR-T cell therapy is used to treat certain blood cancers, and it is being studied in the treatment of other types of cancer. Also called chimeric antigen receptor T-cell therapy.
CAR-T

 

A bone marrow transplant is a medical treatment that replaces your bone marrow with healthy cells. The replacement cells can either come from your own body or from a donor. A bone marrow transplant is also called a stem cell transplant. Transplantation can be used to treat certain types of cancer, such as leukemia, myeloma, and lymphoma, and other blood and immune system diseases that affect the bone marrow.
Stem cells are special cells that can make copies of themselves and change into the many different kinds of cells that your body needs. There are several kinds of stem cells and they are found in different parts of the body at different times.
Stem Cell Transplant

 

Cancer surgery is an operation or procedure to take out a tumor and possibly some nearby tissue. It is the oldest kind of cancer treatment, and it still works well to treat many types of cancer today. A doctor who specializes in cancer surgery is called a "surgical oncologist." Several types of surgery are helpful to people with cancer. Some surgeries are used in combination with other types of treatment. Types of surgeries include: Curative surgery, Preventive surgery, Diagnostic surgery, Staging surgery, Debulking surgery, Palliative surgery, Supportive surgery, and Restorative surgery.
Surgery

 

Chemotherapy is a drug treatment that uses powerful chemicals to kill fast-growing cells in your body. Chemotherapy is most often used to treat cancer, since cancer cells grow and multiply much more quickly than most cells in the body. Many different chemotherapy drugs are available. Chemotherapy drugs can be used alone or in combination to treat a wide variety of cancers.Though chemotherapy is an effective way to treat many types of cancer, chemotherapy treatment also carries a risk of side effects. Some chemotherapy side effects are mild and treatable, while others can cause serious complications.
Chemotherapy

 

Radiation therapy uses high-energy particles or waves, such as x-rays, gamma rays, electron beams, or protons, to destroy cancer cells. Cells normally grow and divide to form new cells. But cancer cells grow and divide faster than most normal cells. Radiation works by making small breaks in the DNA inside cells. These breaks keep cancer cells from growing and dividing and cause them to die. Nearby normal cells can also be affected by radiation, but most recover and go back to working the way they should. Most types of radiation therapy don’t reach all parts of the body, which means they’re not helpful in treating cancer that has spread to many places within the body.
Radiation Therapy

 

Hormone therapy is a treatment that uses medicines to block or lower the amount of hormones in the body to slow down or stop the growth of cancer. Hormones are natural substances made by glands in our bodies. Hormones are responsible for many functions in our body, including the growth and activity of certain cells and organs. The endocrine system is the network of glands that make hormones. Some cancers use hormones to grow or develop. This means the cancer is hormone sensitive or hormone dependent. Hormone therapy for cancer uses medicines to block or lower the amount of hormones in the body to stop or slow down the growth of cancer.
Hormone Therapy

 

 

Targeted therapy is a type of cancer treatment that targets proteins that control how cancer cells grow, divide, and spread. It is the foundation of precision medicine. As researchers learn more about the DNA changes and proteins that drive cancer, they are better able to design treatments that target these proteins. Most targeted therapies are either small-molecule drugs or monoclonal antibodies. For some types of cancer, most patients with that cancer will have a target for a certain drug, so they can be treated with that drug. But, most of the time, your tumor will need to be tested to see if it contains targets for which we have drugs.
Targeted Therapy

 

Cryoablation for cancer is a treatment to kill cancer cells with extreme cold. During cryoablation, a thin, wand like needle (cryoprobe) is inserted through your skin and directly into the cancerous tumor. A gas is pumped into the cryoprobe in order to freeze the tissue. Then the tissue is allowed to thaw. The freezing and thawing process is repeated several times during the same treatment session. Cryoablation for cancer may be used when surgery isn't an option. Cryoablation is sometimes used as a primary treatment for Bone, Cervical, Eye, Kidney, Liver, Lung, Prostate cancer.
Cryoablation

 

Radiofrequency ablation uses an electric current to heat up a small area of nerve tissue to stop it from sending pain signals. It can provide lasting relief for people with chronic pain, especially in the lower back, neck and arthritic joints. Most patients have some pain relief after radiofrequency ablation, but the amount varies by cause of pain and location. Radiofrequency ablation may be right for you if you have chronic pain that does not respond to other treatment, such as pain medication and physical therapy.
Radiofrequency Ablation

 

Hyperthermia is a type of treatment in which body tissue is heated to as high as 113 °F (45 °C)to help damage and kill cancer cells with little or no harm to normal tissue. Hyperthermia to treat cancer is also called thermal therapy. During treatment, the doctor numbs the treatment area and inserts small probes with tiny thermometers into the tumor. Thermometers help the doctor closely watch the temperature of the tumor and nearby tissue during treatment. Hyperthermia can help other cancer treatments, such as chemotherapy and radiation therapy, work better.
Hyperthermia

 

 

 

Photodynamic therapy (PDT) is a treatment that involves light-sensitive medicine and a light source to destroy abnormal cells. It can be used to treat some skin and eye conditions, as well as certain types of cancer. On their own, the medicine and light source are harmless, but when the medicine is exposed to the light, it activates and causes a reaction that damages nearby cells.This allows small abnormal areas of tissue to be treated without the need for surgery. PDT can be used to treat abnormal cells in parts of the body that a light source can reach, such as the skin, eyes, mouth, oesophagus and lungs.
Potodynamic Therapy

 

Clinical trials are research studies that involve people. Through clinical trials, doctors find new ways to improve treatments for people with certain diseases. Researchers design cancer clinical trials to test new ways to treat cancer. Clinical trials are the final step in a long process that begins with research in a lab. Before any new treatment is used with people in clinical trials, researchers work for many years to understand its effects on cancer cells in the lab and in animals. Any time one needs treatment for cancer, clinical trials are an option to think about. Trials are available for all stages of cancer.
Clinical Trials